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Antisometropia refers to a condition where there is a significant difference in the refractive power of the two eyes, specifically that one eye has a hyperopic (plus) refractive error while the other eye has a myopic (minus) refractive error. This condition can cause visual discomfort and issues with binocular vision because the brain receives different focus points from each eye, making it challenging to achieve clear, coordinated vision.

This definition underscores why the option indicating that one eye is plus and the other is minus accurately captures the essence of antisometropia. In contrast, the other options describe scenarios that do not align with this concept. For example, having both eyes with the same refractive error defines isometropia, while both eyes having no refractive error suggests emmetropia, and strabismus pertains to an eye alignment issue, which is unrelated to the concept of refractive differences.